Columbus Crew vs. Inter Miami 2025 MLS Odds, Time, and Prediction

Both Columbus Crew and Inter Miami flying high in the 2025 MLS, but Lionel Messi’s team has hit a sort of bad run. Last weekend, they drew 0:0 with Chicago Fire, which was the first time in almost two years that they failed to score when Messi was a starter.

They need to do better this time around, as a win would get them back to the top of the Eastern Conference table, which is where Columbus Crew currently is.

Columbus Crew vs. Inter Miami 2025 MLS Odds

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When, Where, and How to Watch?

• Place: Lower.com Field in Columbus, Ohio
• Date: Saturday, April 19, 2025
• Time: 6:00 p.m. ET
• How to Watch: Apple TV

The Herons Need to Pull Themselves Together

When Lionel Messi starts for Inter Miami, the Herons almost always score at least a goal. In fact, such a thing happened in every single game from August 31, 2023, to Sunday, April 13, 2025.

So, what went wrong for Messi & Co. last weekend when they drew 0:0 with Chicago Fire? They were completely outplayed by their opponents and should feel lucky for not losing that day.

In fact, they would’ve lost that game if it weren’t for their brilliant goalkeeper Oscar Ustari, who was the man of the match. He went 7-for-7 with his saves, keeping a clean sheet for the first time in the 2025 MLS.

Will he be able to do the same on April 19 against Columbus Crew? We’re not so sure about that as Inter Miami’s next opponent has some really good attackers on the roster.

Reasons Why MLS Odds Favor Columbus Crew

Inter Miami is the best team in the 2025 MLS, with superstars like Lionel Messi, Luis Suarez, and Oscar Ustari. However, these guys are old – they’re all in their late thirties, so you can’t expect consistency from them anymore.

This explains why after a superb run in March, they entered a bad streak in April. Another reason for this is that they’re also competing in the CONCACAF Champions Cup, where they’ve reached the semifinal stage.

Meanwhile, Columbus Crew’s only focus is the 2025 MLS. And they’re doing great in America’s elite soccer league. They’re currently at the top of the Eastern Conference with a 5-3-0 record.

This is no surprise as their roster looks great, especially now after they’ve signed Daniel Gazdag, one of the league’s best playmakers.

Columbus Crew vs. Inter Miami Prediction

Inter Miami’s previous MLS game was somewhat boring, but our prediction is that the next one won’t. Instead, we expect fireworks on April 19.

That said, one of the best picks for the Columbus Crew vs. Inter Miami game is Over 2.5 Goals. After all, we saw three or more goals in each of their last six duels.

Who’s going to score more goals at Lower.com Field on Saturday? We think Columbus Crew, but we’re not 100% confident. If Messi produces magic, anything can happen. That’s why our advice is to stick to goals.

Pick: Over 2.5 Goals